Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers

Exclusion Criteria

• •Patients unable to hold reasonably still on a procedure table or hold their breath during imaging or needle passes
• •Patients with a gross body weight over 375 pounds (upper limit of the CT and angiography tables)
• •Patients with uncorrectable coagulopathy
• •Platelet count \< 30,000/ul
• •International Normalized (INR) \> 1.5
• •Patients with moderate to severe ascites who cannot undergo trans-jugular biopsy or sufficient drainage
• •No clear reachable target for percutaneous or trans-jugular biopsy
• •Patient who cannot have a peripheral blood draw for ctDNA