Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Centre hospitalier de l'Université de Montréal (CHUM)
With
Fonds de la Recherche en Santé du Québec
Canadian Institutes of Health Research (CIHR)
This study will include infected healthcare workers (HCW) and patients for whom a nosocomial infection in CHUM is suspected. The CHUM laboratory is responsible for COVID-19 diagnostic testing in all eligible HCW and patients. After initial diagnosis on standard PCR testing, samples are maintained at -80. Viral RNA is extracted and next-generation sequencing of the viral genome is performed using Nanopore long read sequencing platform. Preliminary data suggest that SARS-CoV-2 has a "molecular clock" of 2 single nucleotide polymorphism (SNP) per month. The analysis and between-isolate comparaison of those SNP among epidemiologically related cases will allow to support or refute the hypothesis of person to person nosocomial transmission. All infected patients will be matched 1:1 with contemporary community cases to provide a viral genome back catalog and better contextualize molecular epidemiology analyses. Molecular clusters will be reported to infection prevention and control teams and resulting interventions will be monitored.
Age
18–100
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Hospitalized in the institution during the study period
Healthcare workers in the institution during the study period
You may not be if
None
Clareo Health | COVID-19 Genomic Sequencing for Nosocomial Outbreak Investigations
