Aging With HIV and Neurocognitive Decline, a Follow-up Study

Inclusion Criteria

• •Having participated in the ANRS EP58 HAND 55-70 study
• •A signed informed consent
• •To be affiliated and benefit from the French Social Security
• •HIV-1
• •Aged between 55 years and 76 years;
• •with a viral load \< 50 copies/mL for more than 24 months (with a minimum of 3 available viral loads 6 months prior to inclusion). Blips -defined by a transient increase in viral load- are allowed if \< 200 copies/mL, with a maximum of two blips within 24 months;
• •With a CD4 (cluster of differentiation 4) count at inclusion ≥ 200 cells/µL for more than the last 12 months (with a last available CD4 count \< 6 months of inclusion);
• •A signed informed consent
• •To be affiliated and benefit from the French Social Security
• •An Isolated HIV-2 infection
• •Confused or with an ongoing neurological disease
• •Presenting psychiatric syndromes interfering with cognitive evaluation;
• •With sensorial loss, analphabetism or language barriers rendering the interpretation of tests difficult.
• •With recent extensive neurocognitive evaluation within 6 months prior to inclusion
• •With neurological disease with ongoing clinically relevant sequela
• •Participating in another research program, prohibiting the participating in additional research
• •Vulnerable: minors, under guardianship or curatorship, or persons deprived of liberty for administrative or judiciary reasons