Age

18–100

Sex

MALE

Healthy volunteers

Not accepted

History of radiotherapy to the pelvis or transurethral resection of the prostate (TURP)
Contraindications for MRI according to the guidelines of the local department of Radiology, inability to lay on a treatment table for 45-60 minutes or severe claustrophobia
Absence of pre-treatment PSMA PET CT
WHO performance score \> 2
International Prostate Symptom Score ≥ 15
PSA \> 30
Prostate volume \>100c

Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy