Office Systolic Blood Pressure between 130 and 159 mmHg and Diastolic Blood Pressure \< 100 mmHg
Body Mass Index (BMI) between 18.5 and 35 kg/m²
Weight stable within ± 5 % in the last three months
No significant change in food habits or in physical activity in the 3 months prior to randomization and agreeing to keep them unchanged throughout the study
You may not be if
Known or suspected secondary hypertension
Known hypertensive retinopathy and/or hypertensive encephalopathy;
History of spontaneous or drug-induced angioedema;
Clinically significant valvular heart disease or severe aortic stenosis
History of acute coronary syndrome (non-ST elevation myocardial infarction, ST elevation myocardial infarction, and unstable angina pectoris), stroke, or transient ischemic attack within 6 months prior to screening
Suffering from a severe chronic disease or gastrointestinal disorders found to be inconsistent with the conduct of the study by the investigator
Clareo Health | To Assess TOTUM-854 on Blood Pressure in Subjects With Moderately Elevated Blood Pressure