COVID-19 Experiences in the SELF Cohort

Background: COVID-19 affected African Americans more than Whites. African Americans, especially women, have had higher rates of COVID-19 infections compared to Whites. They are also more likely to go...

Lead sponsor: National Institute of Environmental Health Sciences (NIEHS)•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

National Institute of Environmental Health Sciences (NIEHS)

Study Description: This cross-sectional study will be an add-on to the Study of Environment, Lifestyle and Fibroids (SELF) (Protocol Number: 10-E-N044). SELF is a prospective cohort study of fibroid development. From November 2010 to December 2012, the study enrolled a volunteer sample recruited from Detroit, MI and surrounding areas of approximately 1,700 African-American women ages 23-35 without a diagnosis of fibroids. SELF has been a rich information source regarding the health of young African-American women. This current COVID-19 study will focus on collecting information regarding SELF participant s experiences throughout the COVID-19 pandemic through a short, one-time online questionnaire. The questionnaire will contain questions on a range of topics related to the COVID-19 pandemic to include 1) pandemic experiences in the following domains: COVID-19 illness of participant (including LONG-COVID), participant s family and friends, participants social community 2) vaccination status, 3) access to health care, 4) employment vulnerabilities and employment loss, 5) challenges with caring for children, 6) financial hardship, coping strategies, 7) sleep problems, and 8) psychosocial stressors. The questionnaire will also ask questions about COVID-19-related symptoms, vaccination, and hospitalizations experienced by the participants and/or members of her household and community. Objectives: Primary Objective: To describe the impact of the COVID-19 pandemic on reproductive-aged African American women and their families. We have three goals: First, these basic data will be summarized in a report that will be sent back to the participants. Like our newsletters, this will serve as a cohort maintenance activity, keeping our participants interested and engaged in the study. Secondly, SELF collaborators are continuing to follow the participants (the 4th follow-up is in progress, and a 5th follow-up is being planned), so these data will allow us to consider the impact of COVID-19 in future analyses. Additional studies with this cohort could also be undertaken in the future. Depending upon the exposure outcome being investigated in the data from those additional follow ups, an overall measure of impact may be important, or the impact on specific domains may be of most interest. Thirdly, we also view this study as an opportunity to document the impact of the COVID-19 pandemic, a once in a century event, in a well characterized group of reproductive-aged African-American women whose health and well-being have been followed for nearly a decade now. This is an understudied group and documenting their response to COVID will serve as one of several case-studies of specific subpopulations that are likely to emerge after the pandemic. The goal is to document the range of adverse impacts experienced and the factors (e.g., low income, limited educational attainment, pre-pandemic health conditions, neighborhood factors) that might mitigate or exacerbate those adverse impacts for this understudied demographic group. Endpoints: Primary Endpoint: Descriptive data on impact of the COVID-19 pandemic on reproductive-aged African American women and their families

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 19, 2026Terms

Trial snapshot

StatusENROLLING_BY_INVITATION

Phase—

Enrollment1,668

Start dateJun 2022

Last updatedFeb 19, 2026

Condition

COVID-19

Locations shown

National Institute of Environmental Health Sciences (NIEHS)

Bethesda, Maryland

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 19, 2026Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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