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UNKNOWNNANCT05359497

Value of MRCP+ And Liver Multiscan in the Management of Dominant Strictures in Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a chronic progressive biliary disease. Due to the heterogeneous disease course and the relatively low clinical event rate of 5% per year it is difficult to pred...

Lead sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)•View source on ClinicalTrials.gov

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Contacts

Tim E Middelburg, MSc

CONTACT

+31648510414 [email protected]

Sponsors

Lead Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Collaborators

Perspectum

After informed consent, patients will undergo standard care with blood tests and MRI/MRCP. While performing the MRI, additional sequences called LMS are performed. Thereafter, an ERCP will be performed. Approximately 8 weeks after ERCP, another MRI/MRCP and LMS will be performed. Also, blood tests will be performed and a clinician will evaluate the clinical condition and complaints of patients Images will be coded and analysed by Perspectum to retrieve MRCP+ and LMS results.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Established diagnosis according to the IPSCSG Definitions (22)
•Age ≥ 18
•Able to give informed consent
•Clinically suspicious for a dominant stricture

Exclusion Criteria

•insufficient image quality
•known allergy for MRI contrast agents

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 4, 2022Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment50

Start dateMay 2022

Last updatedMay 4, 2022

Condition

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 4, 2022Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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