Dietary Impact on Intestinal Sulfate Metabolism

Exclusion Criteria

• •Antibiotic use within 3 months
• •Planned antibiotic therapy within the period of the study, e.g., perioperative antibiotics.
• •Use of sulfonamides or sulfasalazine, as these sulfur-containing medications may confound results
• •Use of 5-aminosalicylates (5-ASA), as they are known to inhibit sulfidogenesis
• •History of anaphylactic food allergies, e.g., peanuts, seafood.
• •Food intolerances and allergies, including gluten sensitivity, lactose intolerance, and intolerance of high fiber dietary content.
• •Strict vegan eating practices, with refusal to consume animal products.
• •Planned use of oral probiotics while on study.
• •Serious, concomitant illness that, in the opinion of the Investigator, would interfere with evaluation of safety or efficacy, or put the participant at risk of harm from study participation.
• •Significant alcohol use, defined as \> 20 g/day in females and \> 30 g/day in males for a period of 3 months within one year prior to screening.
• •Underlying chronic gastrointestinal disease that can cause diarrhea, including short bowel syndrome, irritable bowel syndrome, malabsorption, and celiac disease.
• •History of partial or complete colectomy.
• •History of malabsorptive bariatric surgery.
• •Currently participating in another clinical study.
• •Legally incompetent and unable to understand the study's purpose, significance and consequences, and to make decisions accordingly.