Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer

Inclusion Criteria

• •Age \> 18 years.
• •Able to provide informed consent.
• •Histologic diagnosis of prostate adenocarcinoma.
• •ECOG performance status 0-1.
• •High-risk localized disease by NCCN criteria (\>cT3, Grade group \>4, or PSA \>20 ng/mL) or clinical N1 disease.
• •Clinical M0 by conventional imaging (computed tomography (CT) and bone scan (BS)) and/or molecular imaging (prostate specific membrane antigen (PSMA)- positron emission tomography (PET))