Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vanderbilt University Medical Center
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Males and females of all races between 18 and 65 years of age
Hypertension defined by two or more properly measured seated blood pressure readings \>130/85 mmHg or currently on antihypertensive medication.
Obesity will be defined as having a body mass index (BMI) ≥ 30 kg/m2.
Able and willing to provide informed consent.
You may not be if
Pregnancy or breast feeding
Current smokers or history of heavy smoking (\>2 packs/day)
History of alcohol or drug abuse
Previous allergic reaction to study medications
Type I diabetes.
Cardiovascular disease other than hypertension such as myocardial infarction within 6 months prior to enrollment, presence of angina pectoris, significant arrhythmia, congestive heart failure (LV hypertrophy acceptable), deep vein thrombosis, pulmonary embolism, second or third degree heart block, mitral valve stenosis, aortic stenosis, or hypertrophic cardiomyopathy
History of serious cerebrovascular disease such as cerebral hemorrhage, stroke, or transient ischemic attack
History or presence of immunological or hematological disorders
Impaired renal function
Treatment with chronic systemic glucocorticoid therapy (more than 7 consecutive days in 1 month)
Treatment with any investigational drug in the 1 month preceding the study
Inability to give, or withdraw, informed consent
Other factors which in the investigator's opinion would prevent the subject from completing the protocol (i.e., clinically significant abnormalities on clinical, mental examination or laboratory testing or inability to comply with protocol, inability to find IV access)
Clareo Health | Sympathetic Mechanisms in Obesity-Crossover Design
