ATP Level and Cough Sensitivity to ATP in Subjects With Refractory/Unexplained Chronic Cough

Exclusion Criteria

• •1. smoking currently or in the past 6 months, or a smoking history of \>20 pack-year
• •2. a forced expiratory volume in 1 second/forced vital capacity ratio \<70%;
• •3. use of inhaled/oral corticosteroid, bronchodilators, anti-allergic medicine, antitussive medicine or anti-reflux treatment in the past 1 week;
• •4. a history of acute respiratory infection in the past 4 weeks;
• •5. a history of severe disease (cancer, acute coronary syndrome and so on).
• •1. smoking currently or in the past 6 months, or a smoking history of \>20 pack-year
• •2. a forced expiratory volume in 1 second/forced vital capacity ratio \<70%
• •3. a history of acute respiratory infection in the past 4 weeks
• •4. posstive findings of chest radiography
• •5. a history of chronic respiratory disease and allergic disease
• •6. any signs of cough hypersensitivity