3D Printed Oral Stents for Patients With Head and Neck Cancer Receiving Radiation Therapy

PRIMARY OBJECTIVES: I. To evaluate whether a customized 3 dimensional (3D) printed oral stent achieves non-inferior levels of patient reported outcomes as the standard dental-fabricated oral stents at the time prior to starting treatment. SECONDARY OBJECTIVES: I. To evaluate the performance of the 3D stent on imaging parameters (i.e. mandibular and soft tissue displacement) for degree of normal tissue sparing. II. Evaluate the levels of patient reported outcomes after patients have developed side effects from radiation treatment. III. To evaluate the commercially available TruGuard oral cavity positioning system. OUTLINE: Patients wear a customized 3D printed oral stent over 5-10 minutes in the supine position at the time of radiation simulation, before starting radiation therapy, and in the 3rd to 5th week of radiation therapy. Patients may also optionally wear the commercially-made stent called TruGuard at these timepoints.