MRI Study of High Definition Transcranial Electrical Stimulation in Chronic Tinnitus (MRI HDtES-T)

Exclusion Criteria

• •1. Ages below 18 (neurobiology is quite different in children vs. adults)
• •2. Ages above 75 (cortical excitability changes with age)
• •3. Tinnitus symptoms with known medial origin, including:
• •1. Meniere's disease
• •2. Pulsatile tinnitus
• •3. Acoustic neuroma
• •4. Spontaneous optoacoustic emissions
• •5. Any other known medical origin
• •4. Severe mood disorder (major depression or anxiety)
• •5. Diagnosis of any medical condition potentially affecting brain function, including:
• •1. neuropsychiatric or mental disorders (bipolar, post-traumatic stress disorder, etc.)
• •2. severe mood disorders (major depression or anxiety)
• •3. psychotic states or disorders
• •4. developmental disorders
• •5. neurological disorders, including mild cognitive impairment
• •6. significant head injury
• •7. significant history of alcohol/substance abuse or dependence
• •8. active chronic pain condition (\>1 year duration)
• •9. other major medical conditions (e.g., cancer, stroke).
• •6. MRI contraindications:
• •1. metal or other implants that are not MR-safe
• •2. claustrophobia
• •3. pregnancy or suspected pregnancy
• •7. tDCS contraindications\*:
• •1. skin conditions or injuries on the scalp
• •2. hair extensions, wigs, braids, etc. that cannot be removed prior to the study
• •3. metal implants or pacemakers (also contraindicated for MRI)
• •8. Non-English speakers (due to written consent and questionnaires administered)
• •9. Significant history of alcohol/substance abuse or dependence within last 12 months
• •10. Neurostimulation or neuromodulation treatment longer than 20 minutes within the past 3 months
• •11. Current medication use potentially affecting brain function, including decongestants, antihistamines, benzodiazepines or other anticonvulsants, or anti-psychotics.