Clareo Health | Effect of Oxygen Therapy for Patients With Precapillary Pulmonary Hypertension Who Experience an Altitude Related Adverse Health Effect (ARAHE) During 30h Exposure to 2500m
Effect of Oxygen Therapy for Patients With Precapillary Pulmonary Hypertension Who Experience an Altitude Related Adverse Health Effect (ARAHE) During 30h Exposure to 2500m
Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Zurich
Patients with pulmonary hypertension who reveal an altitude-related adverse health effects at 2500m will be given oxygen therapy by nasal cannula titrated to maintain the oxygen saturation above 90%. The study will investigate, whether this measure will restore altitude-induced impairment to baseline levels at low altitude.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Informed consent as documented by signature
PH class I (PAH) or IV (CTEPH) diagnosed according to guidelines: mean pulmonary artery pressure \>20 mmHg, pulmonary vascular resistance ≥3 wood units, pulmonary arterial wedge pressure ≤15 mmHg during baseline measures at the diagnostic right-heart catheterization
You may not be if
resting partial pressure of oxygen \<8 kilopascal at Zurich at 490 m low altitude
exposure to an altitude \>1000 m for ≥3 nights during the last 2 weeks before the study
