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Quantifying Congestion by Ultrasound | Clinical Trials | Clareo Health

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UNKNOWNNANCT05090137

Quantifying Congestion by Ultrasound

The investigators will determine the feasibility of identifying and quantifying changes in interstitial and intravascular congestion by imaging in participants with heart failure. The investigators wi...

Lead sponsor: NHS Greater Glasgow and Clyde•1 locations•View source on ClinicalTrials.gov

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Contacts

Pierpaolo Pellicori, MD, FESC

CONTACT

+44 0141 330 4744 [email protected]

Sponsors

Lead Sponsor

NHS Greater Glasgow and Clyde

Age

19 - 100 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Clinical diagnosis of heart failure
•Plasma NT-proBNP \>125ng/L or BNP \>35 ng/l
•Left ventricular ejection fraction (LVEF) \<50% on prior imaging test
•Treated routinely with a daily dose of loop diuretic
•Receiving other guideline-indicated therapy for heart failure
•Willing to sign the informed consent form
•Greater than 18 years of age

Exclusion Criteria

•Chronic Kidney Disease Stage 4 or worse (eGFR \<30 mL/min/1.73 m²)
•Atrial fibrillation
•Significant valve disease (investigators opinion)
•Breathlessness or chest pain at rest or minor exertion
•Patients unable to lie flat
•Patients deemed too unstable to miss treatment with diuretics for 48 hours
•Patients taking part in another interventional trial
•Any other concomitant condition that in the opinion of the investigator would not allow a safe participation in the study (ie:-pregnancy, significant frailty)
•Patients unwilling or unable to consent
•For patients willing to undergo MRI; contraindication to MRI including claustrophobia, metalworkers, and intra-orbital or intracranial metal (eg:- stents), and non-MRI compliant device.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 22, 2021Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment20

Start dateNov 2021

Last updatedOct 22, 2021

Condition

Locations shown

NHS Greater Glasgow and Clyde

Glasgow

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 22, 2021Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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