To carry out a comparative assessment of the indices of humoral, cellular immunity and cytokine profile in patients with acute respiratory infections.
Current Program Population: 1500 healthy male and female volunteers, aged of between 18 and 65 will be included in the program.
All included volunteers will be divided into groups:
Group 1 - 750 volunteers who will be vaccinated with BiVac polio vaccine; post-vaccination observation period of 12 months.
Group 2 - 750 volunteers, placebo will be administered, post-vaccination observation period of 12 months.
The probability of getting into one of the two groups for each volunteer will be 50%.