The objectives of the trial are:
1. To test effects of UPLIFT versus BOOST on changes in depressive symptoms (primary outcome) in PWE over 12 months.
2. To test effects of UPLIFT versus BOOST on changes in quality of life and seizures (secondary outcomes) in PWE over 12 months.
3. To test whether intervention effects are mediated by increases in mindfulness and decreases in rumination.
4. To test whether intervention effects are moderated by participant characteristics and facilitator characteristics.
Age
18–99
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
adult (≥18 years of age);
diagnosed with epilepsy for at least one year;
fluent in English or Spanish;
elevated depressive symptoms (PHQ-9 score ≥10);
willing to participate in audiotaped group telephone sessions
You may not be if
severe depressive symptoms (PHQ-9 ≥20);
active suicidal ideation (PHQ-9 item #9 ≥1 or otherwise reported during screening);
active psychotic disorder (psychiatric diagnosis or antipsychotic medications in the EHR);
significant cognitive impairment (indicated in EHR or evident during screening)
Clareo Health | Telephone-Based Support Programs for People With Epilepsy
