Patient age ≥ 18 y/o (No age limit due to cardiac variant Fabry IVS4 in Taiwan symptom of onset could be beyond 60 y/o)
Patient with confirmed chronic kidney disease (CKD 1\~5) diagnosis whose urine protein/creatinine (UPCR) is 150mg/g or above, or urine albumin/creatinine (ACR) is 30mg/g or above.
Patient who are willing to sign inform consent form
You may not be if
Patient who are unwilling to sign inform consent form
Patient who received confirmed diagnosis of Fabry Disease
Patient with known etiology of renal failure diagnosed with renal biopsy.
