1. Patients with a history of asthma

2. Patients with asthma- COPD overlap

3. Patients with serious disease other than COPD

4. Patients with unstable or life-threatening cardiac arrhythmias

5. Patients hospitalized for heart failure or myocardial infarction within 1 year of screening

6. Patients with systolic ejection fraction less than 40%

7. Patients with unstable ischemic heart disease

8. Patients receiving regular oxygen therapy for 1hour or more per day

9. Others who are difficult to participate in the research under judgment of the investigation

Effects of Tiotropium/Olodaterol on Cardio-pulmonary Exercise Capacity in Patients With Hyperinflated Chronic Obstructive Pulmonary Disease [ACHIEVE]