Enalapril Folic Acid Tablets Combined With CCB or Diuretic to Prevent Stroke in Patients With Type H Hypertension

Exclusion Criteria

• •1\. Previous stroke with definite diagnosis;
• •2\. Patients with previous well-diagnosed myocardial infarction;
• •3\. The presence of well-diagnosed heart failure;
• •4\. Postoperative revascularization;
• •5.DBP \>=110 mmHg or SBP \>=180 mmHg;
• •6\. Confirmed secondary hypertension;
• •7\. Severe physical and systemic disease, which is estimated to be unable to complete the follow-up;
• •8\. People with known congenital or acquired organic heart disease;
• •9\. People who have had obvious intolerable adverse reactions to ACEI drugs in the past;
• •10\. Have contraindications to ACEI drugs (including renal failure) or are allergic to the drugs used in the study or other ingredients in the drugs;
• •11\. According to the researchers, there are contraindications to the use of folic acid;
• •12\. Pregnant and lactating women;
• •13\. If there are other obvious laboratory tests, abnormal physical signs and clinical diseases, it is not suitable to participate in the study according to the researcher's judgment;
• •14\. Unwilling to participate in the trial, unwilling or unable to change the existing medication regimen;
• •15\. Long-term use of folic acid or health medicines containing folic acid;
• •16.Severe mental disorder, unable to express their will