First line of the email MUST contain NCT # and Site #.
CONTACT
Lead
Bristol-Myers Squibb
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Fresh pre-treatment and on-treatment tumor biopsy must be provided for biomarker analysis.
Measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 and at least 1 lesion accessible for biopsy. Fine needle biopsy, cytology, and bone lesion biopsies are not acceptable.
Eastern Cooperative Oncology Group Performance Status of 0 or 1.
Radiographically documented progressive disease on or after the most recent therapy.
Received standard-of-care therapies, (except for Part 1C, 2C and 2D, where participants with prior docetaxel use for the advanced/metastatic setting will be excluded), including an available programmed death (ligand)-1 inhibitor known to be effective in the tumor type for which they are being evaluated.
Advanced or metastatic disease and have received, be refractory to, not be a candidate for, or be intolerant of existing therapies known to provide clinical benefit for the condition of the participant.
You may not be if
Women who are pregnant or breastfeeding.
Primary central nervous system (CNS) malignancy.
Untreated CNS metastases.
Leptomeningeal metastases.
Concurrent malignancy requiring treatment or history of prior malignancy active within 2 years prior to the first dose of study treatment.
Active, known, or suspected autoimmune disease.
Condition requiring systemic treatment with either corticosteroids within 14 days or other immunosuppressive medications within 30 days of the first dose of study treatment.
Prior organ or tissue allograft.
Uncontrolled or significant cardiovascular disease.
Major surgery within 4 weeks of study drug administration.
History of or with active interstitial lung disease or pulmonary fibrosis.
