About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Retinal Changes in Vitamin D Deficiency | Clinical Trials | Clareo Health

Back to clinical trial search

COMPLETEDNANCT04891211

Retinal Changes in Vitamin D Deficiency

Retinal tissue parameters of pediatric patients with vitamin D deficiency will be evaluated in this prospective case-control study. The patients will be divided into 2 groups according to the vitamin ...

Lead sponsor: Adiyaman University•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Adiyaman University

The study of the relationship between vitamin D status and retinal diseases is a new concept, and there is a large gap in research focusing on the pediatric population in the literature. The importance of vitamin D in retinal maturation and its role in the development of retinal diseases at a young age is being investigated. In this sense, as far as known, it is the first study investigating retinal structure parameters in pediatric patients with vitamin D deficiency.

Age

8 - 17 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. age \<18 years old
•2. serum vitamin D \[(25(OH) D), calcitriol\] level \<20 ngr/mL in previous two weeks
•3. visual acuity \>20/20
•4. manifest refraction spherical equivalent \<3D
•5. normal biomicroscopic and fundus examination.

Exclusion Criteria

•1. history of any chronic ocular diseases, except for refractive error (e.g., uveitis, glaucoma, retinopathy of prematurity)
•2. history of ocular surgery (e.g., cataract, strabismus, open globe injury, laser photocoagulation)
•3. having an ocular abnormality (e.g., persistent fetal vasculature, optic disc hypoplasia, fovea plana)
•4. history of systemic diseases that have the potential to affect ocular tissues (e.g., diabetes mellitus, Graves' disease, albinism, Down syndrome, Fabry diseases, Wilson syndrome)
•5. history of any systemic diseases that can affect the serum vitamin D level (e.g., parathormone or calcium metabolism disorders)
•6. already receiving vitamin D treatment.

Related studies

COmparison of Clarus and Optos Ultrawide Field Imaging Systems for Inherited Retinal Disease

NCT06380075 · Retinal Disease

RECRUITINGPhase 1/2

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

NCT06789445 · Primary Photoreceptor Disease, Retinitis Pigmentosa (RP), and more

RECRUITINGPhase 3

The VITDALIZE Study: Effect of High-dose Vitamin D3 on 28-day Mortality in Adult Critically Ill Patients

NCT03188796 · Critical Illness, Vitamin D Deficiency, and more

Intraoperative OCT Guidance of Intraocular Surgery II

NCT03713268 · Macular Holes, Epiretinal Membrane, and more

Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight

NCT05694689 · Vitamin D Deficiency

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 18, 2021Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment150

Start dateFeb 2021

Last updatedMay 18, 2021

Condition

Pediatric Disorder Vitamin D Deficiency Retinal Disease Choroidal Disease Optic Nerve Diseases

Locations shown

Adıyaman U

Adıyaman, None Selected

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 18, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions