Short-term Effectiveness of Gabapentin Versus Placebo in Acute Lumbosacral Radiculalgia by Herniation Disc (GRADE)

Exclusion Criteria

• •Motor neurological deficit (≤ 3/5) or cauda equina syndrome (emergency surgical indications),
• •Chronic neuropathic pain in the lower limb affected by radiculalgia,
• •Lumbar infiltration performed within 72 hours prior to inclusion or unable to be performed after 72 hours,
• •Patient already on Gabapentin or Pregabalin, or having taken these treatments in the 7 days prior to inclusion
• •Contraindication to Gabapentin (Hypersensitivity to the active substance or to any of the excipients: corn starch, talc, yellow iron oxide, titanium dioxide, sodium lauryl sulfate, gelatin, shellac, propylene glycol, black iron oxide and potassium hydroxide)
• •Creatinine clearance \< 30ml/min,
• •Hemodialysis patient,
• •Body weight \< 50kgs,
• •Transplant patient
• •Patient under guardianship or curatorship
• •Pregnant or breastfeeding woman