Study of Trifarotene Cream to Assess Risk of a Trophic Acne Scar Formation

Inclusion Criteria

• •Participant with clinical diagnosis of acne vulgaris on the face as defined by (excluding the nose and middle zone of approximately 2 centimeter \[cm\]):
• •1. Investigator's Global Assessment (IGA) score of 3 (Moderate) or 4 (Severe), with the same score on both sides of the face; and
• •2. A minimum of 20 inflammatory lesions (papules and pustules) in total with at least 10 on each side; and
• •3. No more than 2 nodules (greater than or equal to \[\>=\] 1 cm in diameter) on the face; and
• •4. A minimum of 10 atrophic acne scars in total (\>2 mm)
• •Participant with a symmetrical number of the following lesions/scars on the whole face:
• •1. Inflammatory and non-inflammatory lesions; and
• •2. Atrophic acne scars (minimum of 4 scars per half-face)
• •The participant is a female of non-childbearing potential
• •If a female of childbearing, potential uses oral contraceptives that are also approve for treating acne vulgaris