Impact of GSE and Xylitol (Xlear) on COVID-19 Symptoms and Time to PCR Negativisation in COVID-19 Patients

Exclusion Criteria

• •Patients with Severe symptoms: Hypoxia (SpO2 \<88% not corrected by 2 lt nc oxygen) plus severe shortness of breath (excluded)
• •Patient with very low viral load (threshold cycle \[Ct\] \> 25 per PCR).
• •Known hypersensitivity to one of the constituents, particularly to xylitol or GSE
• •Under 18 years of age
• •Women of childbearing age who are pregnant, breastfeeding mothers, and intend to become pregnant during the study period; unwilling/unable to take a pregnancy test.
• •Unable to provide informed consent or decline to consent or unwillingness to adhere to the Standard of Care protocol.
• •Patients with severe symptoms -Hypoxia (SpO2 \<88% not corrected by 2 liter non- concentrated oxygen) plus severe shortness of breath
• •History of immunodeficiency or are currently receiving immunosuppressive therapy.
• •Have had a planned surgical procedure within the past 12 weeks.
• •Already part of this trial, recruited at a different hospital.
• •Patient unable to perform oro-nasopharyngeal decolonization
• •Patients with acute exacerbation of severe comorbidities like heart disorders Chronic Obstructive Pulmonary Disease (COPD), Heart Failure New York Heart Association (NYHA) Class 3 and 4 and/or diseases with severe oxygenation problems
• •Patients on Remdesivir and/or other clinical trials.