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UNKNOWNNANCT04833543

Verticalization Robotic Exoskeleton DoC

Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but t...

Lead sponsor: Memorial Hermann Health System•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Memorial Hermann Health System

Age

18 - 75 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. unresponsive wakefulness syndrome/vegetative state (UWS/VS) or minimally conscious state (MCS) following traumatic brain injury (TBI), intracerebral bleeding, ischemic infarction, or hypoxic brain injury
•2. Medical clearance by a physician
•3. 18-75 years old
•4. Mobilization into standing for at least 10 minutes without signs of orthostasis

Exclusion Criteria

•1. Time since injury less than 4 weeks or more than 6 months
•2. Mobilization into standing lasts more than 30 minutes
•3. Severe osteoporosis
•4. Muscle tone that prevents joint motion (Modified Ashworth Scale (MAS) 4)
•5. Unstable fractures
•6. Decubiti on areas contacted by robotic mobility device (i.e. heels, tibia, greater trochanter, ischial tuberosity, sacrum)
•7. Inability to fit device requirements\*
•* Height 4'8"-6'4", Weight 88-222 lbs., Hip Flexion 0-90˚, Knee Flexion 0-90˚, Plantigrade

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 1, 2021Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment10

Start dateApr 2021

Last updatedSep 1, 2021

Condition

Brain Injuries Disorder of Consciousness

Locations shown

TIRR Memorial Hermann

Houston, Texas

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 1, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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