Second Affiliated Hospital, Zhejiang University, School of Medicine
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
The subject has metastatic colorectal cancer, and the first and second-line standard treatments have failed
There is at least one target lesion that can be treated with HIFU
Voluntarily accept this treatment clinical research, and sign the "Subject Informed Consent"
18-75 years old, no gender limit
The level of physical strength of the Eastern Cooperative Oncology Group (ECOG): PS\<=2
The expected survival time is greater than 3 months
No chemotherapy or radiotherapy within 21 days before enrollment
The function of major organs is basically normal
You may not be if
Pregnant or lactating women
People infected with HIV, hepatitis C virus and Treponema pallidum
There is an active infection that requires systemic treatment (such as active tuberculosis)
Severe infection within 4 weeks before starting the study treatment
Subjects who have received allogeneic tissue/solid organ transplantation
The patient suffers from major vascular disease or irregular bleeding disease
Suffer from physiological or pathological malnutrition diseases, chronic diarrhea, cachexia, etc.
The patient has autoimmune diseases, such as (but not limited to) multiple sclerosis, systemic lupus erythematosus and inflammatory bowel disease, vitiligo
The patient has a history of serious drug or food allergy (for example, allergy to protein)
The patient has serious heart disease (including but not limited to: myocardial infarction, cardiomyopathy, valvular disease, malignant arrhythmia, etc.), severe liver and kidney damage, uncontrolled blood sugar and blood pressure (the subject's blood pressure, After using antihypertensive drugs, it still cannot be controlled within the normal range; fasting blood glucose is still \>10mmol/L after using antihypertensive drugs)
The patient has uncontrollable seizures or loss of insight due to mental illness
In the 12 months before screening, the patient has a history of drug abuse, drug abuse, and long-term alcoholism
Within 3 months before screening, the patient is participating in other clinical studies
Other situations that cannot participate in clinical research.
Clareo Health | Study of the Safety and Effectiveness of HIFU Combined With REGOTORI for Metastatic Colorectal Cancer
