PeRsonalIzed remOtely Guided Preventive exeRcIse Therapy for a healThY Heart

Inclusion Criteria

• •treated or untreated patients with hypertension (blood pressure 130/80 - 159/99 mmHg) AND/OR
• •Patients with prediabetes (impaired fasting glucose and/or insulin resistance) with either:
• •Fasting plasma glucose: 100 to 125 mg/dL (5.6-6.9 mmol/L) Hemoglobine A1c: 5.7% to 6.4% Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) index above 75% of population distribution (\>2.0) AND/OR
• •Patients with obesity with 30 kg/m² ≥ body mass index ≤ 42 kg/m²
• •Patients with subclinical signs of diastolic dysfunction without symptoms (HF Stage B disease)
• •Men and women with diagnosis of HF stage C: i.e. patients who have a total score ≥ 5 points according to the recent recommendation paper on how to diagnose heart failure with preserved ejection fraction from the Heart failure Association of ESC.
• •All participants should be on optimal medical treatment and stable with regard to symptoms and pharmacotherapy for at least 4 weeks before enrollment in the study. All participants should have internet access at home.