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Stellate Ganglion Block and Cerebral Vasospasm | Clinical Trials | Clareo Health

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UNKNOWNNANCT04691271

Stellate Ganglion Block and Cerebral Vasospasm

At present, cerebral vasospasm (cVS) is the main cause of delayed cerebral infarction (DCI), which leads to high disability and mortality rate after aneurysmal subarachnoid hemorrhage. As a consequenc...

Lead sponsor: Beijing Tiantan Hospital•1 locations•View source on ClinicalTrials.gov

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Contacts

Ruquan Han, M.D., Ph.D

CONTACT

8610-59976660 [email protected]

Sponsors

Lead Sponsor

Beijing Tiantan Hospital

Cerebral vasospasm refers to the extensive segmental or diffuse contraction of cerebral vasculature after aSAH, and cerebral blood flow is significantly reduced, which can lead to delayed cerebral ischemia (DCI) or delayed ischemic neurological dysfunction (DIND). Past studies have shown that if cerebral vasospasm occurs in patients with aSAH, the proportion of ischemic brain injury can be as high as 20%-30%.Obviously, prevention and treatment of CVS are the key to reducing the disability and mortality of aSAH.

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age range: 18-65 years old;
•Within 48 hours after onset of aSAH,and planning surgical treatment(aneurysm clipping);
•Preoperative Hunt-Hess grade 2-3
•Sign informed consent.

Exclusion Criteria

•ASA \> grade III;
•Patients with posterior circulation aneurysm, ophthalmic aneurysms or internal carotid aneurysms;
•patients with multiple aneurysms;
•Patients with severe coagulation dysfunction;
•Patients with trauma and local infection in the nerve block area;
•Local anatomic structure changes (neck structure changes caused by radiotherapy, chemotherapy and surgery);
•MCA stenosis or infarction was found by preoperative imaging;
•Patients with poor temporal window signal revealed by preoperative TCD (clear waveform image could not be obtained);
•Allergy to known local anesthetics;
•Pregnant and lactating women.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: March 15, 2024Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment202

Start dateJul 2021

Last updatedMar 15, 2024

Condition

Aneurysmal Subarachnoid Hemorrhage Stellate Ganglion Block Cerebral Vasospasm

Locations shown

Beijing Tiantan Hospital

Beijing, Beijing Municipality

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 15, 2024Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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