Synovial Fluid Sleep Study

Exclusion Criteria

• •1. History of blood-borne diseases including HIV, HBV, HCV, HTLV, or syphilis
• •2. Pregnant
• •3. Multiligamentous knee injury
• •4. Concomitant meniscal repair, meniscal allograft transplantation, osteotomy, or repair of focal chondral defect (e.g., osteochondral autograft transfer system, osteochondral allograft, matrix-induced autologous chondrocyte implantation)
• •5. Prior ipsilateral knee surgeries or injuries
• •6. Primary sleep disorders including insomnia, sleep apnea, or restless legs syndrome
• •7. Uncontrolled psychiatric disorders with sleep disturbance
• •8. Night shift work
• •9. Travel with time zone change within three weeks of surgery
• •10. Systemic inflammatory disease
• •11. Autoimmune disease
• •12. Immunomodulatory drug use
• •13. Chemotherapy within a year before surgery
• •14. Intra-articular injection within 3 months before surgery