Validation of In-Ear Sensor

Exclusion Criteria

• •Subject is considered as being morbidly obese (defined as BMI \>39.5)
• •Compromised circulation, injury, or physical malformation of fingers, toes, hands, ears or forehead/skull or other sensor sites which would limit the ability to test sites needed for the study. (Note: Certain malformations may still allow subjects to participate if the condition is noted and would not affect the particular sites utilized.)
• •Females who are pregnant, who are trying to get pregnant or who have a urine test positive for pregnancy on the day of the study (For Induced Febrile Subjects only)
• •Subjects with known respiratory conditions such as:
• •* uncontrolled / severe asthma,
• •* flu,
• •* pneumonia / bronchitis,
• •* shortness of breath / respiratory distress,
• •* respiratory or lung surgery,
• •* emphysema, COPD, lung disease
• •Subjects with self-reported heart or cardiovascular conditions such as:
• •* Resting high blood pressure: systolic \>140 mmHg or diastolic \>90 mmHg on 3 consecutive readings (For Induced Febrile Subjects only)
• •* have had cardiovascular surgery
• •* chest pain (angina)
• •* heart rhythms other than a normal sinus rhythm or with respiratory sinus arrhythmia
• •* previous heart attack
• •* blocked artery
• •* unexplained shortness of breath
• •* congestive heart failure (CHF)
• •* history of stroke
• •* transient ischemic attack
• •* carotid artery disease
• •* myocardial ischemia
• •* myocardial infarction
• •* cardiomyopathy
• •Self-reported health conditions as identified in the Health Assessment Form
• •* diabetes,
• •* thyroid disease (controlled and uncontrolled)
• •* kidney disease / chronic renal impairment,
• •* history of seizures (except childhood febrile seizures),
• •* epilepsy,
• •* history of unexplained syncope,
• •* recent history of frequent migraine headaches,
• •* recent head injury within the last 2 months,
• •* Cancer / chemotherapy
• •Subjects with medical inflammatory conditions/taking antiinflammation medications
• •* Barbiturates
• •* Antipsychotics
• •* Recent immunizations (within 1 month)
• •* Subjects who have taken antipyretics in the last 240 minutes (aspirin, acetaminophen, ibuprofen)
• •Other known health condition, should be considered upon disclosure in health assessment form