Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of North Carolina, Chapel Hill
With
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patient self-report of at least 1 cup urine/24-hours
Age ≥18 years
Receipt of thrice weekly in-center HD at a participating clinic (UNC-associated Carolina Dialysis- Carrboro, Siler City, Pittsboro, Sanford, and Lee County)
≥60 days receiving in-center HD
Willingness to take study medication and undergo study testing
Ability to provide informed consent
You may not be if
Known allergy to loop diuretic
History of poor adherence to HD or medical regimen per nephrologist
\>1 hospitalization in prior 30-days
Frequent hypotension (systolic BP \<80 mmHg at \>30% of HD treatments in prior 30-days)
Cirrhosis per nephrologist
Hearing disorder per nephrologist
Serum potassium \<3.5 mEq/L, magnesium \<1 mg/dL, or corrected calcium \<8 mg/dL in prior 30-days
Taking a non-loop diuretic (e.g. spironolactone, eplerenone, ethacrynic acid, thiazides)
Taking an aminoglycoside, cisplatin, methotrexate, cyclosporine, adrenocorticotropic hormone (ACTH), lithium, phenytoin, or oral/intravenous steroid
Natural licorice consumption
Prisoners, patients with significant mental illness
Pregnant patients and nursing mothers
Clareo Health | Pilot Study of Loop Diuretics Among Individuals Receiving Hemodialysis