Quantification of Clinically Relevant Drug Induced Changes in HbO2 Affinity

Exclusion Criteria

• •Any drug intake within 10 days prior to blood collection
• •Smoking
• •Haemoglobinopathy
• •Acute inflammatory disease within 14 days prior to blood collection
• •Pregnancy or breastfeeding
• •Severe trauma or blood loss within 14 days prior to blood collection
• •Participation in any other clinical study
• •High altitude sojourn for several days (\> 3,000 m) within four weeks prior to blood collection