Ivermectin in Adults With Severe COVID-19.

Inclusion Criteria

• •Over 18 years old.
• •Confirmed diagnosis of SARS-CoV-2 by polymerase chain reaction (PCR).
• •Diagnosis of severe pneumonia according to criteria of the National Institute of Health and the Colombian Consensus (suspected respiratory infection, organ failure, arterial oxygen saturation (SaO2) ambient air \<90% or respiratory rate \> 30 resp/min) or diagnosis of acute respiratory distress syndrome according to criteria of the National Institute of Health and the Colombian Consensus (clinical findings, bilateral radiographic infiltrates, + oxygenation deficit as well: mild: 200 mmHg \< PaO2/FiO2 (fraction of inspired oxygen) \< 300 mm/Hg; moderate: 100 mm/Hg \< PaO2/FiO2 \< 200 mm/Hg and, severe: PaO2/FiO2 \< 100 mm/Hg).
• •Less than 14 days since the onset of symptoms.
• •Hospitalized in a general internal medicine ward, special care unit, or those designated for managing patients with COVID19.