Effect of Intraoperative Iloprost Inhalant on Hemodynamic Stability in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery

Exclusion Criteria

• •Emergency operation
• •Patients undergoing minimally Invasive Direct Coronary Artery Bypass
• •Patients with cardiogenic shock or ventricular-assist device (eg. ECMO, IABP)
• •Patients with pre-existing infections prior to surgery (eg. sepsis)
• •Patients with liver cirrhosis
• •Patients with hemorrhagic disease / bleeding risk (history of active peptic ulcer, intracranial hemorrhage, congenital hemorrhagic disease etc.)
• •Patients with cerebrovascular event (TIA, stroke) within 3 months
• •Patients with symptomatic asthma/chronic obstructive pulmonary disease who are receiving treatment such as inhaler or steroid
• •Patient with severe chronic kidney disease (GFR(CKD-EPI) \<30ml/min/1.73m2)
• •Patient with acute kidney injury
• •Patients who have participated in other clinical studies that may affect prognosis
• •Patients who cannot understand the informed consent (eg. Foreigner)