Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Virginia
With
Children's Hospital of Philadelphia
Age
10–20
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Ability to provide informed consent (or assent for minors)
Relapsing-remitting MS diagnosis per 2017 McDonald criteria
Ages ≥ 10 years to ≤ 20 years
Diagnosis of MS or first clinical symptom of MS (whichever comes first) within ≤ 36 months from the time of enrollment.
Ability to provide informed consent (or assent for minors)
Age-, sex-, \& BMI-matched to pediatric MS subjects (1:1 allocation)
Healthy children and young adults from the local communities
You may not be if
Progressive form of MS
Patients with an active, chronic disease of the immune system other than MS
Conditions affecting the central nervous system (CNS) white matter (e.g. leukodystrophy) or for whom another condition may better explain imaging abnormalities (e.g. lupus)
Myelin oligodendrocyte glycoprotein (MOG) antibodies on serologic testing
Corticosteroid exposure within 30 days of study enrollment
History of past imaging or neurologic event raising concern for any inflammatory CNS process
Medical history or previous/current diagnosis consistent with an autoimmune disorder pertaining to any system of the body (e.g. diabetes mellitus type 1, Crohn's disease, lupus)
