Effect of Enhanced Sweat Rate on the Safety and Edema Status of Chronic Edematous Patients

Exclusion Criteria

• •Phase 1: Healthy subjects:
• •1. Subject is enrolled to another clinical investigation that might interfere with this study
• •2. Subject is pregnant or planning to become pregnant within the study period, or lactating mothers
• •3. Subject has no known sensitivity to Neoprene
• •Phase 2: CHF Patients:
• •1. Subject is enrolled to another clinical investigation that might interfere with this study
• •2. Subject is admitted to the hospital for acute decompensated or acute heart failure
• •3. Subject has any known lower body skin problems (open wounds, ulcers)
• •4. eGFR\<15 ml/min/m2
• •5. Subject with severe peripheral arterial disease
• •6. Subject is pregnant or planning to become pregnant within the study period, or lactating mothers
• •7. Subject has known sensitivity to Neoprene