About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

UNKNOWNPhase 1NCT04566757

Safety and Efficacy of Human Umbilical Cord Blood Plasma Infusion for Age-Related Cognitive Decline

This study is designed to investigate the safety of Umbilical Cord Blood Plasma infusions in elderly adults regardless of gender, with age-related cognitive decline. Human clinical data of the use of ...

Lead sponsor: American Academy of Regenerative Medicine•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

American Academy of Regenerative Medicine

Age

65 - 85 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Age 65-85 years old
•2. Evidence of cognitive decline on neuro-cognitive testing
•3. Able to participate in research trial for 12 months
•4. Women must have documented menopause or infertility determination
•5. Ability to receive intravenous infusions
•6. Patient or legally authorized representative able to sign informed consent

Exclusion Criteria

•1. Patients receiving any other investigational biologics or drugs
•2. History of transfusion reaction
•3. Dementia related to specific pathology (Alzheimer's Disease, Alcohol-related, etc.)
•4. Inability to participate in cognitive or performance testing
•5. History of cancer in the last 5 years
•6. History of infectious disease within the previous 12 months
•7. Severe kidney (eGFR\< 30) and heart failure (Class III/IV)
•8. History of Human Immunodeficiency Virus Infection
•9. History of Hepatitis B, or C
•10. History of immunosuppressive therapy
•11. History of organ transplantation
•12. Difficulty of obtaining peripheral venous access
•13. Allergy to histamine blockers
•14. Inability to participate in the clinical trial at any data collection and end points
•\-

Related studies

Cardiac-Control Affecting Learning Through Mindfulness (CALM)

NCT06410157 · Age-related Cognitive Decline, Alzheimer Disease

Older Breast Cancer Patients: Risk for Cognitive Decline

NCT03451383 · Cancer, Breast, Age-related Cognitive Decline, and more

Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB

NCT05599490 · Age-related Cognitive Decline

Development of an Innovative Health Ingredient From Marine By-products for the Healthy Aging

NCT04910399 · Memory Impairment, Age-related Cognitive Decline

Brain Aging: Muscle-to-brain Axis Modulates Physio-cognitive Decline

NCT05828043 · Age-related Cognitive Decline, Age-related Physiology Decline

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 13, 2021Terms

Trial snapshot

StatusUNKNOWN

PhasePHASE1

Enrollment12

Start dateMar 2021

Last updatedJan 13, 2021

Condition

Age-related Cognitive Decline

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 13, 2021Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions