Efficacy of Personalized Exercise Program and Trimetazidine in Rehabilitation of Patients After RFA of AF

Exclusion Criteria

• •Congenital and acquired heart defects.
• •Acute coronary syndrome (unstable angina, myocardial infarction), myocardial revascularization during the previous 6 months
• •Transient ischemic attack, stroke in history.
• •Arterial hypertension (BP ≥160/100 мм. рт. ст.)
• •The risk of thromboembolic complications on a scale CHA2DS2-VASc\> 2
• •Risk of hemorrhagic complications of anticoagulant therapy (HAS-BLED\> 3 points on the scale).
• •Complications after RFA.
• •Chronic heart failure above III FC (NYHA), ejection fraction (EF) \<40%.
• •Acute thrombophlebitis, complicated forms of varicose veins (thrombophlebitis, phlebothrombosis).
• •Pronounced atherosclerosis of peripheral arteries (intermittent claudication), requiring surgical intervention.
• •Violation of conductivity: AV-blockade 2-3 degrees, complete blockade of the bundle of the His bundle
• •The presence of an implanted pacemaker pacemaker / pacemaker with a resynchronization function/cardioverter-defibrillator)
• •Conduct RFA on AF earlier.
• •The presence of a history of syncopal states.
• •Diabetes mellitus type 1 and 2 in the stage of decompensation.
• •Acute conditions: infection, exacerbation of chronic diseases in a period of less than 1 month prior to the study; severe injury, surgical interventions other than RFA for a period of less than 2 months from the start of the study
• •Renal failure (creatinine levels above 300 µmol / L or 3.5 mg / dL).
• •Patient's refusal to participate in the study
• •Alcohol and drug abuse.
• •Peptic ulcer and duodenal ulcer in history.
• •Obesity, body mass index (BMI) ≥40 kg / m2
• •Intake of Trimetazidine MB and its analogues for 3 months. before inclusion in research.
• •The presence of any disease that, according to the doctor, prevents the inclusion of the patient in the study.
• •unable to understand study instructions
• •with considerable illness in the musculoskeletal system or with physical disability, which complicates exercise training