About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNCT04472312

Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver Transplantation

Liver transplantation is the standard treatment for chronic advanced liver disease, whether or not associated with a primary liver tumor. The intraoperative bleeding and the need for blood transfusion...

Lead sponsor: Centre hospitalier de l'Université de Montréal (CHUM)•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

METHODS Objectives The primary objective will be to measure the hemodynamic effects of vasopressin on portal pressure in cirrhotic patients who have had a hypovolemic phlebotomy during a liver transplant. The secondary objectives will be to measure the effects of vasopressin on portal pressure in patients who have not had a phlebotomy and to compare this effect between patients who have or have not had a hypovolemic phlebotomy. The tertiary objective will be to assess the effect of the variation in portal pressure under vasopressin, associated or not with a hypovolemic phlebotomy, on hemorrhagic clinical outcomes (intraoperative bleeding and blood transfusions).

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Cirrhotic patients undergoing a liver transplantation
•18 years and older
•Planned use of vasopressin during the surgery

Exclusion Criteria

•Fulminant or sub-fulminant hepatitis without underlying chronic liver disease
•Anesthetic plan does not include the use of vasopressin (contraindication or not relevant according to the anesthesiologist)

Related studies

Natural History of Noncirrhotic Portal Hypertension

NCT02417740 · Cystic Fibrosis, Immunologic Deficiency Syndrome, and more

Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement

NCT07439939 · Liver Cirrhosis, Portal Hypertension

3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

NCT06205992 · Cirrhosis, Liver Portal Hypertension

Sexual Dysfunction in Cirrhosis

NCT05428267 · Sexual Dysfunction in Patients With Cirrhosis Awaiting Liver Transplantation

Rectus-Intercostal Fascial Plane Block for Liver Transplantation Donors

NCT07233096 · Liver Transplantation, Living Donor, and more

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: July 22, 2022Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment60

Start dateAug 2020

Last updatedJul 22, 2022

Condition

Liver Transplantation Portal Hypertension Blood Transfusion Blood Loss, Surgical

Locations shown

Centre Hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 22, 2022Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions