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DNA Repair in Patients With Stable Angina. | Clinical Trials | Clareo Health

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UNKNOWNNCT04453267

DNA Repair in Patients With Stable Angina.

Markers of DNA damage and repair are present in both atherosclerotic plaques and peripheral blood mononuclear cells of patients with coronary artery disease. A positive correlation has been observed b...

Lead sponsor: University Hospital Southampton NHS Foundation Trust•1 locations•View source on ClinicalTrials.gov

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Contacts

Thomas R Gilpin, MBBCh

CONTACT

0044 (0)2380777222 [email protected]

Zoe Nicholas, BSc

CONTACT

0044 (0)2380777222 [email protected]

Sponsors

Lead Sponsor

University Hospital Southampton NHS Foundation Trust

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age ≥18 years
•Ability to provide written informed consent

Exclusion Criteria

•Age ≥ 80 years
•Inability to provide written informed consent
•Presentation with an acute coronary syndrome
•Severe valvular heart disease
•Hypertrophic cardiomyopathy
•Left ventricular ejection fraction ≤ 35%
•Prior coronary revascularisation (surgical or percutaneous)
•Diabetes Mellitus
•Clinical evidence of peripheral vascular disease
•Prior history of cerebrovascular disease
•Malignancy
•Active inflammatory disorders (e.g. rheumatoid arthritis/connective tissue disorder)
•Renal impairment eGFR \<60ml/min/1.73m2
•Anaemia (Hb \<100g/dL)

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 28, 2022Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment172

Start dateFeb 2020

Last updatedOct 28, 2022

Condition

Coronary Artery Disease Coronary Arteriosclerosis DNA Damage DNA Repair Abnormality

Locations shown

University Hospital Southampton NHS Foundation Trust

Southampton, Hampshire

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 28, 2022Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions