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Physiologic MR Imaging of Salivary Gland Tumors | Clinical Trials | Clareo Health

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RECRUITINGNANCT04452162

Physiologic MR Imaging of Salivary Gland Tumors

The goal of this study is to use advanced Magnetic Resonance Imaging (MRI) techniques to help identify the difference between cancerous and non-cancerous salivary gland tumors for improving treatment ...

Lead sponsor: Abramson Cancer Center at Penn Medicine•1 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Marisa Sanchez

CONTACT

2159019994 [email protected]

Lisa Desiderio

CONTACT

610-721-3365 [email protected]

Sponsors

Lead Sponsor

Abramson Cancer Center at Penn Medicine

Collaborators

McCabe Fund

The goal of this proposed study is to investigate the potential utility of combined analysis of parameters (Ktrans, ti and ADC) in discriminating benign from malignant salivary glands tumors (SGTs). A total of 30 treatment naïve patients suspicious of SGT as observed on clinical evaluation and prior routine CT, MRI, Ultrasound, FNAC and/or PET will undergo 3T MRI. The MRI protocol will include acquisition of anatomical images with and without contrast agent injection, diffusion imaging and dynamic contrast enhanced-MRI.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Possess a salivary gland lesion of 1cm3 size
•Have no prior history of treatment for salivary gland lesion

Exclusion Criteria

•Has any prior history of cancer other than SGT
•Has any MRI contra-indications
•Has a history of known renal disease.
•Has history of prior radiation to head and neck region
•Is pregnant

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: September 9, 2025Terms

Trial snapshot

StatusRECRUITING

PhaseNA

Enrollment30

Start dateAug 2020

Last updatedSep 9, 2025

Condition

Salivary Gland Tumor

Locations shown

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 9, 2025Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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