co-morbidity precluding pancreatectomy

chronic neuropathy ≥ grade 2

WHO performance score \> 2

granulocyte count \< 1500 per cubic millimetre

platelet count \< 100 000 per cubic millimetre

serum creatinine \> 1.5 UNL (upper limit normal range)

albumin \< 2,5 g/dl

female patients in child-bearing age not using adequate contraception, pregnant or lactating women

mental or physical disorders that could interfere with treatment of with the provision of informed consent

any reason why, in the opinion of the investigator, the patient should not participate

Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer (NORPACT-2)