Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
A.O. Ospedale Papa Giovanni XXIII
With
Aferetica - Italy (BO)
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Plasma Ig Donors
Adult (\>18 and \<65-yr-old) men and women
Convalescent donor who recovered from COVID 19 from at least 14 days according to the clinical and laboratory criteria defined by the Consiglio Superiore di Sanità on February 20, 2019 ("The recovered patient is the one who resolves the symptoms of COVID-19 infection and who is negative in two consecutive tests for the search for SARS-Cov-2, performed 24 hours apart") with the exceptions mentioned in the attached derogation (that is "no upper age limit to donation provided there are no clinical contraindications to the procedure and independent of documented evidence of two negative tests for SARS-Cov 2 naso-faringeal contamination")
Male or female donor; if female only if nulliparous; in both cases with a negative history of blood component transfusions
Careful clinical evaluation of the patient-donor with particular reference to the criteria established by current legislation to protect the health of the donor who donates by apheresis
Presence of adequate levels of neutralizing anti-SARS-COV-2 antibodies;
Biological qualification test negative defined by current indications (performed at SIMT of HPG23)
Test negative for: HAV RNA, HEV RNA, PVB19 DNA (performed at HPG23)
Informed consent
Recipients
Adult (\>18-yr-old) men and women
COVID-19 pneumonia diagnosed by standard criteria
Need of ventilator support
Informed consent for participation in the study (critically ill patients will be unable to provide consent. Consent will be oral if a written consent will be impossible. If the subject is incapable of giving an informed consent and an authorized representative is not available without a delay that would, in the opinion of the Investigator, compromise the potential life-saving effect of the treatment this can be administered without consent. Consent to remain in the research should be sought as soon as the conditions of the patient will allow it).
\<48 hours of mechanical ventilation
You may not be if
\>48 hour mechanical ventilation
Patient being treated with other anti-COVID-19 experimental treatments
