Lead Sponsor

Rigshospitalet, Denmark

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

No

•Patients between 18-80 years
•Confirmed HCoV-19 infection
•Temperature above 38.0o C
•Pulmonary symptoms and signs, at least one of the following before clinical decision for intubation and respirator treatment:
•1. Respiratory distress, RR ≥ 30/min;
•2. Oxygen saturation ≤ 93% at rest state;
•3. Arterial partial pressure of oxygen (PaO2) / Fraction of inspiration O2 (FiO2) ≤ 300mmHg, 1mmHg=0.133kPa
•Pneumonia that is judged by chest radiograph or computed tomography
•In respirator and possible for treatment within the first 24 hours

•Patients that have need for additional immunosuppressive treatment
•Patients with any past (within the past 3-5 years) or present malignancy (other than excised basal cell carcinoma).
•Co-Infection with other infectious agent.
•Females capable of becoming pregnant must have a negative pregnancy test prior to treatment. After inclusion, they must use contraceptives for 2 months following the given stem cell treatment. The pill, spiral, depot injection of progesterone, sub-dermal implantation, hormonal vaginal ring and transdermal patch regarded as safe contraceptives.
•Patients who are participating in other clinical trials.