Biktarvy in Treatment-Naïve Late Presenters With HIV-1 Infection

Exclusion Criteria

• •1. A new AIDS-defining condition diagnosed within the 30 days prior to screening
• •2. Participants experiencing severe organ lesion.
• •3. Positive serum pregnancy test or planned to be pregnant.
• •4. Females who are breastfeeding
• •5. With carcinoma
• •6. Concomitant medication of immunosuppression or chemoradiotherapy
• •7. Participation in any other interventional clinical trial
• •8. Screening stage find: Hb \< 9g/dL, WBC \< 3000/ul. neutrophilic granulocyte\< 1500/ul, PLT\< 75000/ul. Scr \> 1.5 ULN,Hepatic transaminases (AST and ALT) and ALP \> 3 × ULN,total bilirubin ≤ 2 x ULN.
• •9. Any other clinical condition or prior therapy that, in the opinion of the Investigator, would make the subject unsuitable for the study or unable to comply with dosing requirements