Acute Kidney Injury in Polytrauma Patients in Intensive Care Unit

• Study Population: 60 cases of polytrauma patients who have ISS\>15. * Inclusion Criteria: * Age from 18 to 70 years old males or females * Injury Sensitivity Score (ISS \>15 ) * Exclusion Criteria: Patients have end stage liver disease, end stage kidney disease, disseminated malignancy or decompensated heart failure. Sample size :the calculated sample size is 60 cases of trauma patients. • All patients' data will be recorded on admission and daily for 7 days: * Vital signs (blood pressure, heart rate, respiratory rate, body temperature). * Lab investigations: complete blood count, international normalized ratio, prothrombin time, arterial blood gases, kidney function tests, liver function tests, creatine kinase, creatine kinase-muscle band, creatinine clearance, serum sodium, serum potassium and serum phosphorus will be requested for all patients at admission then daily follow up by creatine kinase, creatine kinase-muscle band, kidney function tests, serum sodium, serum potassium and serum phosphorus for 7 days. Glasgow Coma Scale (GCS), Injury Severity Score (ISS),Urine output (ml/kg/h),RIFLE criteria.,Length of ICU and hospital stay,28 days mortality.