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COMPLETEDNANCT04261452

Heart Failure Worsens Muscle Strength in COPD

The combination of heart failure (HF) and chronic obstructive pulmonary disease (COPD) is highly prevalent, but underdiagnosed and poorly recognized. It has been suggested that the decline in function...

Lead sponsor: Mayron Faria de Oliveira•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Mayron Faria de Oliveira

Collaborators

Coordination for the Improvement of Higher Education Personnel

Age

30 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•non-cachectic sedentary patients
•moderate-to-severe COPD according to GOLD classification (FEV1/ FVC \<0.7 and predicted post-bronchodilator FEV1 between 30% and 80%)
•no clinical or echocardiographic evidence of HF for the COPD group
•echocardiographic evidence of HF with reduced left ventricular ejection fraction (\<40%) for the overlap group
•chronic dyspnoea (MRC scale score 2-4)
•NYHA class 2 or 3.

Exclusion Criteria

•long-term O2 therapy
•recent (within a year) rehabilitation program
•osteomuscular limitation
•type I or non-controlled type II diabetes mellitus
•peripheral arterial disease associated with claudication
•Patients with preserved ejection fraction HF

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 7, 2020Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment50

Start dateAug 2014

Last updatedFeb 7, 2020

Condition

COPD CHF Muscle Weakness

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 7, 2020Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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