Cryotherapy for the Prevention of Taxane-Induced Sensory Neuropathy of the Hands and Feet in Breast Cancer Patients

Inclusion Criteria

• •Patients \>= 18 years of age with a diagnosis of breast cancer
• •Patients receiving 12-18 weeks of chemotherapy with a taxane-based regimen (4 cycles of weekly x 3 paclitaxel or 4-6 cycles of docetaxel every 3 weeks)
• •Absence of sensory peripheral neuropathy, skin or nail disorders at the start of treatment
• •Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
• •Ability to complete questionnaires by themselves or with assistance
• •Ability to give signed informed consent