Reporting unbearable urge for self-injury and / or active NSSI behaviour) upon admittance, or on the preceding week.
Not pregnant, nor breast feeding
No history of drugs abuse
No previous treatment with ketamine
No psychotic disorder, nor severe physical condition (including unstable hypertension, arrhythmias or severe / active neurological condition)
You may not be if
Age \< 18 year; Age \>65 years
Men
Inability to sign informed consent, Non-Fluent in Hebrew.
No report of NSSI, last NSSI event took place further than preceding week
Active pregnancy or breast feeding
History of drugs abuse
Previous trial involving ketamine treatment during which no improvement was observed.
Presence of psychotic disorder, and / or major physical condition (including unstable hypertension, arrhythmias or severe / active neurological condition).
